![]() ![]() That study was led by a University of Connecticut researcher and appeared in the peer-reviewed journal Clinical Infectious Diseases, a publication of the Infectious Diseases Society of America. Tess Lawrie, who is one of the study’s co-authors and a BIRD leader, told PolitiFact in an email that her study "shows that large reductions in deaths from COVID are probable when ivermectin is used, especially when employed as early treatment."Īnother meta-analysis, published June 28, arrived at an opposite conclusion. Gorski also pointed out that the researchers, despite claiming to have no conflicts of interest, are affiliated with BIRD (British Ivermectin Recommendation Development) Group.īIRD describes itself as "campaigning for the safe medicine ivermectin to be approved to prevent and cure COVID-19 around the world." This is a good indication that the drug probably doesn’t work." It’s only the smaller, lower-quality trials that have been positive. He added: "The few existing higher quality clinical trials testing ivermectin against the disease uniformly have failed to find a positive result. "Pooling data from a large number of small, low-quality clinical trials does not magically create one large, high-quality clinical trial," wrote Gorski, who is also managing editor of Science-Based Medicine, a website that evaluates medical claims. David Gorski, a professor of surgery and oncology at Wayne State University and chief of breast surgery at the Karmanos Cancer Institute, who has criticized the June study. Some of the studies analyzed in the ivermectin meta-analysis were not peer reviewed, said Dr. "That can be a real problem, and raise unrealistic expectations for a drug that might be very promising or useful, but not a homerun," Morse said. For instance, some insisted that hydroxychloroquine was "a cure," but there hasn’t been strong supporting data for it, he said. Some drugs initially seem promising, but don’t hold up in more rigorous clinical testing, Morse said. "It is only with rigorously designed randomized control trials that any true benefit can be discovered."Īssuming the meta-analysis is correct, ivermectin "would seem to merit further study," said Stephen Morse, an epidemiology professor at Columbia University Medical Center. "In general, most of the ivermectin studies that purport to show a positive benefit are of low quality and have potential sources of bias," which is why the drug is not recommended by the National Institutes of Health or the Infectious Diseases Society of America, he said. Amesh Adalja, a senior scholar at the Johns Hopkins University Center for Health Security, said the study is a meta-analysis (an analysis of other analyses) "whose strength is dependent on the underlying studies that comprise it." Here’s what we know about the study generating favorable headlines of the drug as a way to prevent or treat COVID-19.Įxperts said the trials that the study relies on are not high quality.ĭr. Ivermectin, which is FDA-approved to treat conditions caused by parasitic worms and parasites such as lice, in large doses "is dangerous and can cause serious harm." Food and Drug Administration says ivermectin should not be used to prevent or treat COVID-19. The World Health Organization, in its COVID-19 treatment guidelines, says: "We recommend not to use ivermectin in patients with COVID-19 except in the context of a clinical trial," citing "very low certainty evidence" about the drug. Despite their connection to the group, the authors declared in the study they had no conflict of interest. Moreover, the study was done by researchers affiliated with a group that is campaigning for ivermectin to be approved for COVID-19 use. It is a review of trials done with ivermectin on COVID-19 patients. The headline exaggerates, given that the study says only that fewer deaths might be possible. "New study links ivermectin to ‘large reductions’ in COVID-19 deaths," reads one headline on the Epoch Times. Many of the studies had small sample sizes and other limitations.Īt the same time, ivermectin has not been universally dismissed as a potential treatment.Ī new study has reignited the debate, making claims about fewer coronavirus deaths even though public health authorities say more research is needed. Some limited studies suggested that ivermectin can help treat COVID-19 others show no significant impact. ![]() We’ve rated False claims such as "mountains of data" show ivermectin "basically obliterates" COVID-19 transmission. Is the anti-parasitic drug ivermectin a "cure" for COVID-19? ![]()
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